A well-known polynucleotide treatment, sometimes called a “skin healer”, used to strengthen the skin barrier and improve texture, elasticity and hydration.
Rejuran is a polynucleotide treatment widely recognised for its role in strengthening the skin barrier and improving overall resilience. Dr Ellie Sateei offers Rejuran at her London and Sevenoaks clinics for patients wanting a regenerative approach to skin texture and elasticity.
It is often described as a skin healing treatment, reflecting its focus on the condition of the skin rather than on volume or contour.
Rejuran is an injectable treatment containing polynucleotides derived from purified salmon DNA, processed to a medical standard so that the resulting fragments are recognised by human tissue as a repair signal.
Once introduced into the skin, these fragments support fibroblast activity, encouraging collagen and elastin production, improving hydration retention and helping to calm inflammation. Formulations exist for general facial use and for the delicate eye area.
Rejuran is commonly used for dull, dehydrated or tired-looking skin, fine lines, uneven texture and reduced elasticity. It is also used where the skin barrier feels compromised, including reactive or sensitised skin, and around the eyes where thin skin is a concern.
Dr Sateei will assess your skin during consultation to determine whether Rejuran’s barrier-focused, regenerative approach suits your concerns.
Treatment is delivered through a series of fine injections spread across the treatment area. Topical numbing is usually applied beforehand, and most patients describe mild discomfort.
Small raised points are visible immediately after treatment and typically settle within several hours. Some mild swelling or bruising is common for a day or two. A course of three to four sessions, spaced two to four weeks apart, is typically recommended, with improvements building over the following months.
Dr Sateei uses regenerative injectables where they genuinely suit the skin in front of her, rather than as a default. With more than twenty years in dermatology and aesthetics, she will explain clearly what Rejuran is likely to change and over what timescale.
Every course is tailored to your specific concerns following a thorough consultation, at both her London clinic near Harley Street and her Sevenoaks clinic in Kent.
Rejuran is an injectable polynucleotide treatment that supports the skin’s own repair, improving texture, elasticity and hydration.
It contains polynucleotides derived from purified salmon DNA, processed to a medical standard for use in the skin.
Common concerns include dullness, dehydration, fine lines, uneven texture, reduced elasticity and a compromised skin barrier.
Topical numbing is usually applied beforehand, and most patients describe mild discomfort.
Small raised points are visible immediately and settle within several hours, with mild swelling or bruising possible for a day or two.
A course of three to four sessions, spaced two to four weeks apart, is typically recommended.
Improvements build progressively across the course and continue over the following months.
It is often chosen for reactive or sensitised skin, though suitability is confirmed at consultation.
Yes, dedicated formulations exist for the delicate skin around the eyes.
Most adults wanting to improve skin quality, texture and resilience are suitable candidates, confirmed following a skin assessment.
Rejuran is one of several polynucleotide brands Dr Ellie Sateei uses, alongside Plinest and Nucleofill, each of which has its own page. Plinest is lighter and purely regenerative, while Nucleofill has a firmer, more tightening character.
The full list of other polynucleotide brands used across the clinic is on the polynucleotides (PDRN) page.
Brands named above that have their own page, for linking: Polynucleotides (PDRN) (/brands/polynucleotides), Plinest (/brands/plinest), Nucleofill (/brands/nucleofill)
Rejuran strengthens the skin barrier and improves elasticity, so it suits reactive and tired-looking skin. These are the concerns Dr Ellie Sateei treats with it most often.
If you would like to strengthen and improve the quality of your skin, Dr Ellie Sateei welcomes a personal consultation at her London or Sevenoaks clinic.
Our London clinic is located at 91a New Cavendish Street, London, W1W 6XF
We serve patients from London, Kent and the home counties as well as from all over the world. Our London clinic sits in the heart of Marylebone, within easy reach of the West End by tube, while our Sevenoaks clinic in Ightham is moments from the M25 and M26 for patients across Kent.
