
A regenerative skincare technology built on growth factors from stem cell science, applied after microneedling to make the most of the skin’s natural repair window.

Calecim Professional is a regenerative skincare technology built around growth factors derived from stem cell science, designed to support the skin’s own repair and renewal. Dr Ellie Sateei offers Calecim Professional at her London and Sevenoaks clinics as part of a considered, evidence-based approach to skin health.
Because it supports the skin’s own biological processes, Calecim Professional is often used to enhance recovery and results following other in-clinic treatments.
Calecim Professional uses a concentrate of growth factors derived from umbilical cord lining stem cells. Rather than introducing live cells into the skin, the treatment delivers the beneficial signalling molecules these cells naturally produce, supporting the skin’s own repair and collagen production processes.
The technology has been the subject of clinical research into skin healing and rejuvenation, and is generally applied topically following a procedure that opens the skin’s absorption pathway.

Calecim Professional is commonly used to support skin recovery and quality after procedures such as microneedling, where the skin’s repair response is already active. It is also used more generally to support skin resilience, hydration and radiance, particularly for skin that has become dull or is recovering from previous treatment.
Dr Sateei will assess your skin during consultation to determine whether Calecim Professional is a suitable addition to your treatment plan.
Calecim Professional is typically applied directly to the skin following a procedure such as microneedling, when the skin is most receptive. The application itself is gentle and comfortable, with no significant sensation beyond what is felt during the primary treatment.
There is no separate downtime associated with the application itself, beyond any downtime from the accompanying procedure. Most patients notice the skin looks calmer and more supported in the days following treatment.

Dr Sateei brings over two decades of experience in dermatology and aesthetics to every treatment plan, and only recommends regenerative technologies such as Calecim Professional where they are genuinely likely to support your skin’s needs. Her approach favours working with the skin’s own biology, rather than overriding it.
Every plan is tailored to your individual skin type and goals following a proper consultation, at both her London clinic near Harley Street and her Sevenoaks clinic in Kent.

Calecim Professional is a regenerative skincare treatment using growth factors derived from stem cell science to support the skin’s repair processes.
Its higher gel density gives it a more noticeable tightening quality alongside the regenerative signalling common to the category.
It is most often used alongside microneedling, applied while the skin’s natural repair response is active.
The application itself is gentle. Any discomfort relates to the accompanying procedure, such as microneedling, rather than Calecim Professional itself.
There is no separate downtime from the application, beyond any downtime associated with the primary treatment.
Many patients notice calmer, more supported-looking skin within days, with results building further over the following weeks.
Most adults wanting to support skin recovery, hydration and resilience are suitable candidates, confirmed following a skin consultation.
It is most effective when paired with a procedure that opens the skin’s natural repair pathway, such as microneedling.
Both are regenerative, signalling-based technologies. Dr Sateei will discuss which is best suited to your skin during consultation.
This depends on your skin’s condition and goals, and will be discussed as part of your personalised plan.
Calecim Professional is one of several exosome and growth factor based regenerative brands Dr Ellie Sateei uses, alongside AnteAGE Biosomes, which has its own page. Both are most often applied following SkinPen microneedling, which also has its own page.
The other exosome brands used across the clinic for comparable results are ASCEplus, ExoCoBio, Purasomes, Benev, Ameela Exosomes, ExoHealer, Exoxe, Kimera and ExoCel Bio. All work by delivering regenerative signalling molecules to the skin, with the brand chosen as part of your treatment plan.
Brands named above that have their own page, for linking: AnteAGE Biosomes (/brands/anteage-biosomes), SkinPen microneedling (/brands/skinpen-microneedling)
Calecim Professional is applied while the skin’s repair response is already active, so it supports the result of the treatment it accompanies. These are the concerns Dr Ellie Sateei uses it for most often.



If you would like to support your skin’s natural repair and resilience, Dr Ellie Sateei welcomes a personal consultation at her London or Sevenoaks clinic.
Our London clinic is located at 91a New Cavendish Street, London, W1W 6XF
We serve patients from London, Kent and the home counties as well as from all over the world. Our London clinic sits in the heart of Marylebone, within easy reach of the West End by tube, while our Sevenoaks clinic in Ightham is moments from the M25 and M26 for patients across Kent.